You are here:HOME>News>Export>Source and Multi-Industry Applications of β-Dextran

Source and Multi-Industry Applications of β-Dextran

Time:2023-11-15 Hits:103
Seebio's β-Dextran, as an immune-enhancing dietary fiber component, has gained significant attention. In addition to boosting the body's immune function, β-Dextran can increase the fiber content of food, reduce the use of sugar and fat while maintaining the original texture and taste, meeting the demands of a healthy diet. With the growing awareness of health and focus on functional ingredients, the demand for β-Dextran is expected to continue to rise in the coming years.
β-Dextran is a natural dietary fiber composed of glucose monomers linked together in a polysaccharide chain. It is found in various plants and microorganisms, including grains, fungi, algae, and more. Depending on the source, the structure and functions of β-Dextran can vary. β-Dextran possesses various bioactivities, including immune regulation, anti-tumor, antibacterial, antioxidant, anti-aging, radiation protection, anti-inflammatory, blood sugar reduction, and blood lipid reduction, among others. It has found extensive applications in pharmaceuticals, functional foods, food additives, cosmetics, and animal feed.
The advantages of β-Dextran in regulating food texture and taste, reducing the use of sugar and fat, align with the demand for a healthy diet. With the increasing health consciousness and attention to functional ingredients, the demand for β-Dextran is expected to continue to grow in the coming years. Several countries, including the United States, Canada, Finland, Sweden, China, Japan, and South Korea, have already approved β-Dextran as an effective immune activator, earning it the reputation of a "golden substance" in the field of immunity. β-Dextran activates immune cells by binding to receptors, promotes the production of cytokines, increases antibody levels, activates the complement system, thereby enhancing the body's resistance to foreign pathogens and microbial invasion, and promoting tissue repair.
Source and Regulations of β-Dextran
β-Dextran from different sources, such as grains, yeast, bacteria, algae, and plants, all play important roles in immune regulation. These characteristics include blood sugar and lipid reduction, maintaining intestinal health, enhancing immune function, and improving food properties.
β-Dextran from grain sources, such as barley, oats, and rye, is composed of glucose units linked by β-1,3 or β-1,4-glucosidic bonds. Its main functions include lowering blood sugar and lipids, as well as maintaining intestinal health. The β-Dextran in rice belongs to non-starch polysaccharides, which can hinder the digestion and absorption of starch, proteins, and other substances, regulate blood sugar and lipids, and reduce the risk of cardiovascular diseases. Additionally, β-Dextran in rice can regulate immunity, enhance macrophage activity, and phagocytic capacity.
In China, oat β-Dextran was approved in 2014 for use as a new food ingredient. Furthermore, oat β-Dextran has obtained GRAS certification from the U.S. FDA. In the European Union, β-Dextran from oats and barley has been approved as a new food ingredient, with a health claim stating, "may reduce cholesterol levels in the blood, contributing to the reduction of postprandial blood glucose rise." Oat β-Dextran can be used in various common foods and is suitable for addition to meal replacement products such as cereal bars and shakes due to its prebiotic effects and enhanced satiety.
β-Dextran from Yeast and Fungi Sources:
β-Dextran derived from yeast and Hericium erinaceus (lion's mane mushroom) is connected through β-1,3- and β-1,6-glucose linkages, while Ganoderma spore uses β-1,3-, β-1,4-, and β-1,6-glucose linkages. Their primary function is to enhance immune function. Yeast β-Dextran is present in the yeast cell wall and is insoluble in water. It can bind to specific receptors, enter the lymphatic system through phagocytosis, and thus play an immunoregulatory role. Yeast β-Dextran can specifically bind to macrophages, stimulate and activate immune factors, enhancing immune function.
In 2010, China approved β-Dextran from brewing yeast as a new food ingredient, and in 2012, β-Dextran from baker's yeast was approved as a nutritional fortifier for use in infant formula and children's milk powder. Yeast β-Dextran and β-Dextran from black yeast have received GRAS certification from the U.S. FDA. Additionally, β-Dextran from Ganoderma mycelium has also obtained GRAS certification. The European Union has also approved yeast β-Dextran as a new food ingredient.
As an important functional food ingredient, yeast β-Dextran has been widely used in functional foods and dietary supplements to enhance immunity. Moreover, yeast β-Dextran has the ability to improve the water retention, stability, and emulsification of food. Therefore, it can be used as a fat substitute in dairy products, meat products, baked goods, and other foods.
β-Dextran from Bacterial Fermentation:
β-1,3/α-1,3-Dextran is a novel water-soluble extracellular polysaccharide primarily derived from sucrose through the fermentation, alcohol precipitation, filtration, separation, drying, and grinding processes involving Poria cocos. It consists of a linear chain structure formed by 7 β-1,3-glycosidic bonds and 2 α-1,3-glycosidic bonds, with over 75% of the structure comprised of β-1,3 bonds. Compared to traditional β-Dextrans, β-1,3/α-1,3-Dextran exhibits better water solubility, is colorless, tasteless, highly stable, and has better processing performance, making it suitable for addition to various foods and beverages. Additionally, it has higher activity and immune-enhancing properties.
Research indicates that β-1,3/α-1,3-Dextran has multifaceted functions, including regulating gut microbiota, repairing intestinal mucosa, enhancing immunity, promoting bowel movements, lowering blood sugar and lipids, alleviating fatigue, and repairing liver damage. These findings highlight β-1,3/α-1,3-Dextran as a potent functional ingredient.
β-Dextran from Algae Sources:
A polysaccharide composed of glucose units linked by β-1,3-glucose bonds, β-Dextran from algae primarily functions to enhance immune function. Algae β-Dextran shares similar structural and functional characteristics with yeast β-Dextran and can be used as an immunomodulator. In recent years, algae β-Dextran has gained attention as a new food ingredient due to its high content, typically ranging from 30% to 70%. Compared to yeast-derived β-Dextran, algae β-Dextran has a linear 1,3 structure, making it easy to isolate and purify, meeting consumer demands for natural and minimally processed ingredients. According to relevant regulations, algae β-Dextran can be applied to food and beverages, excluding infant food.
β-Dextran from Plant Sources:
A β-Dextran called plant wound healing Dextran, mainly composed of β-1,3-glucose bonds, exists in plant cell walls. It rapidly accumulates after plant injury, participating in cell wall repair and defense reactions. It possesses various biological activities such as antioxidant, anti-tumor, anti-inflammatory, and antibacterial properties, making it suitable for preparing functional foods or drugs.
Applications of β-Dextran in the Food, Pharmaceutical, and Cosmetic Industries
Food Industry Applications
The increasing consumer focus on immunity has led to heightened attention to β-Dextran in the food and dietary supplement industries, with its applications expanding in functional foods, pharmaceuticals, and cosmetics. With growing health consciousness and demand, the market prospects for β-Dextran are expected to remain promising.
Blood Sugar Regulation: β-Dextran has demonstrated blood sugar-lowering effects, potentially by repairing damaged pancreatic islet B cells and reducing the absorption of exogenous glucose. Additionally, it possesses functions such as antioxidation, intestinal mucosal protection, and lipid reduction. These studies provide a theoretical basis for the application of β-Dextran in the field of blood sugar regulation.
Food Additives: β-Dextran has extensive potential applications in the field of food additives, serving as fillers, thickeners, water-retaining agents, binding agents, and emulsion stabilizers. Research is focused on exploring new applications of β-Dextran in foods and its nutritional and health benefits.
Bread Making:In bread production, β-Dextran can improve the texture, increase volume, enhance hardness and chewiness, delay bread aging, and reduce the glycemic index. In other foods such as baked goods, yogurt, and meat products, β-Dextran also plays a role in improving texture and functionality.
Functional Foods:β-Dextran plays a multifaceted role, not only exhibiting functions such as cell repair, reduction of sugar absorption, and antioxidation in blood sugar regulation but also improving food texture and providing specific functionalities in the field of food additives. These studies present new opportunities for the development of functional foods.
Pharmaceutical Industry Applications
β-Dextran holds vast application potential in pharmaceutical research, playing a role in tumor immunotherapy, vaccine development, and potentially in the diagnosis of fungal infections.
Tumor Immunotherapy: In tumor immunotherapy, β-Dextran can initiate cytotoxic reactions by recognizing iC3b on the surface of tumors, acting as a vaccine adjuvant to enhance immune effects. It activates immune cells suppressed by tumors, regulates the expression of tumor-related genes, and exerts anti-tumor effects.
Vaccine Adjuvant: As a vaccine adjuvant, β-Dextran can be recognized by immune cells, activating the immune system, enhancing immune sensitivity, antibody production, and improving the immune effects of vaccines. β-Dextran particles can efficiently carry vaccine antigens and maintain good immune stimulatory activity.
Cosmetic Industry Applications
β-Dextran is a cosmetic additive that not only promotes the activity of skin cells to achieve skincare effects but also possesses strong moisturizing properties and anti-inflammatory activity, making it suitable for various cosmetic products.
Biological Activity and Skin Regeneration: β-Dextran exhibits significant biological activity, penetrating the skin and activating Langerhans cells. This activation promotes the production of cytokines, growth factors, and vascular endothelial growth factors, leading to skin repair, regeneration, and reduction of wrinkles.
Outstanding Moisturizing Properties:β-Dextran showcases excellent moisturizing capabilities, quickly achieving water-locking and moisturizing functions, surpassing traditional moisturizers. Additionally, it possesses anti-inflammatory and anti-allergic activities, contributing to the reduction of skin issues.
Versatile Potential in Cosmetic Development:In cosmetic research and development, β-Dextran demonstrates broad potential. Its biological activity enables multiple skincare benefits, coupled with powerful moisturizing capabilities, making it suitable for various skincare products.
Application in Hair Care and Body Care Products: The characteristics of β-Dextran also make it suitable for use in shampoos, conditioners, and body care products. It can provide additional nourishment and moisture, repairing dry and rough skin or scalp, and improving related issues.
Future research directions include further exploring the biological activity mechanisms of β-Dextran, optimizing its application in cosmetics, and combining it with other ingredients such as plant extracts to enhance efficacy.
For more product details, please contact us: or Phone: +86 21 58183719 or Wechat: +86 158 0195 7578
Product ID
Product Name
Oat β-Dextran, Cosmetic Grade
Exhibits endogenous moisturizing, skin barrier repair, and can be applied in personal care products for hydration, anti-wrinkle, sensitive skin, sun protection, and after-sun care in forms like gels, moisturizing creams, and masks.
Oat β-Dextran, Food Grade
Mainly found in the subaleurone cell walls of oat grains, it holds nutritional value and is an essential functional ingredient in the food industry.
Water-Soluble Oat β-Dextran Powder
A water-soluble dietary fiber that hinders the digestion and absorption of substances like starch and protein, providing favorable physiological activity.
Chlorella β-Dextran, Purity 70%
In vitro and animal studies show its potential in triggering key immune cells, promoting cytokine secretion, and delivering nutritional support.
β-1,3-Dextran, a neutral polysaccharide, serves as a substrate for identifying, differentiating, and characterizing Dextranases.
Dextran Sulfate Sodium Salt, MW 40,000 (DSS)
Dextran Sulfate Sodium Salt, MW 40,000 (DSS), CASN: 9011-18-1, used as a colitis model animal reagent.
Dextran 10
Dextran 10, a low molecular weight dextran.
Dextran 110
Used in biochemical research.
Dextran 20
Dextran 20, used in biochemical research.
Dextran 200
Used in biochemical research.
Dextran 3
Used in biochemical research.
Dextran 3500
Used in biochemical research.
Dextran 5
Dextran, also known as right-handed glycoside, is a low oligosaccharide composed of several glucose molecules. Gel made from dextran is often used for biochemical separation, such as column chromatography.
Dextran 50
Dextran 50, utilizes molecular sieves for peptide separation, desalting, cleaning biological extracts, and molecular weight determination.
Dextran 500
Dextran 60
Dextran 60, molecular weight 60,000, a high molecular weight dextran used in biochemical research.
Dextran 70
Dextran, produced by fermentation of sugar cane with Leuconostoc mesenteroides. Soluble in water. Slightly soluble in ethanol. Stable in neutral solutions, hydrolyzed under strong acid or elevated temperatures, and oxidized in alkaline solutions.
Dextran T4
Dextran T4 used in biochemical research. Cell studies, precipitation reaction.
DEAE Dextran
DEAE-Dextran can be used as a medium in DNA transfection procedures. It is considered a simple and effective material.
Related Products