Artemisinin

Artemisinin is mainly directly extracted from Artemisia apiacea, or firstly extract the higher content of artemisinic acid out then get the product through semi synthesis technique. Despite from Artemisia apiacea, there is not other natural plant resources containing artemisinin ever found.

Properties: It is colorless acicular crystal, taste bitter.

It is easily soluble in acetone, benzene, chloroform, ethyl acetate and acetic acid, soluble in ethanol, methanol and mineral ether, almost insoluble in water.

Melting point: 156-157 ℃(decompose after decoction with water)

Assay: ≥99%

Qualification:

Item	Specifications	Results
Assay dry base）	≥99.0%	99.6%
Identification	Positive reaction	Positive reaction
Specific rotation[α]20D	+75°~+78°	+77°
Melting point	150℃~153℃	151.3℃~152.6℃
Clarity	≤level 1
Loss on drying	≤0.5%	0.08%
Residue on ignition	≤0.1%	0.06%
Related substances	Conform	Conform
Appearance	White needle crystals	White needle crystals

Storage: It should be stored at room temperature(18~25℃). It should be protected from moisture.

Function and application:

It’s mainly used to control symptoms of febris tritaea and falciparum malaria

It also can treat chloroquine resistant strains and severe falciparum malaria, such as cerebral malaria, Icteric falciparum malaria etc.

It is also used to treat patients with systemic cazenave's lupus and lupus erythematosus discoidcs.

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